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human t lymphoblastic leukemic cell line (ccrf-cem)  (CEM Corporation)

 
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    CEM Corporation human t lymphoblastic leukemic cell line (ccrf-cem)
    Human T Lymphoblastic Leukemic Cell Line (Ccrf Cem), supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccrf-cem+human+leukemic+t+cell+line/ccrf+cem+cells/pm26778657-207-0-6
    Average 90 stars, based on 1 article reviews
    human t lymphoblastic leukemic cell line (ccrf-cem) - by Bioz Stars, 2026-10
    90/100 stars

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    Article Title: Simvastatin regulates non-neuronal cholinergic activity in T lymphocytes via CD11a-mediated pathways.
    Article Snippet: Lymphocyte function associated antigen-1 (LFA-1; CD11a/CD18) is an important mediator of leukocyte migration and T cell activation.. We previously showed that antithymocyte globulin stimulates an independent, non-neuronal cholinergic system in T cells via LFA-1mediated pathways, as evidenced by increases in acetylcholine (ACh) synthesis and choline acetyltransferase (ChAT) mRNA expression.. The cholesterol-lowering drug simvastatin inhibits LFA-1 signaling by binding to an allosteric site on CD11a (LFA-1 α chain), which leads to immunomodulation.

    Expressing:

    Article Title: Simvastatin regulates non-neuronal cholinergic activity in T lymphocytes via CD11a-mediated pathways.
    Article Snippet: Lymphocyte function associated antigen-1 (LFA-1; CD11a/CD18) is an important mediator of leukocyte migration and T cell activation.. We previously showed that antithymocyte globulin stimulates an independent, non-neuronal cholinergic system in T cells via LFA-1mediated pathways, as evidenced by increases in acetylcholine (ACh) synthesis and choline acetyltransferase (ChAT) mRNA expression.. The cholesterol-lowering drug simvastatin inhibits LFA-1 signaling by binding to an allosteric site on CD11a (LFA-1 α chain), which leads to immunomodulation.

    other:

    Article Title: Mediatophore regulates acetylcholine release from T cells.
    Article Snippet: a Department of Pharmacology, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, 97-1 Minamihokodate, Kodo, Kyotanabe, Kyoto 610-0395, Japan b Division of Anatomy and Neuroscience, Department of Morphological and Physiological Sciences, University of Fukui Faculty of Medical Sciences, 23-3 Matsuoka-Shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui 910-1193, Japan c Research Institute of Pharmaceutical Sciences, Musashino University, 1-1-20 Shinmachi, Nishitokyoshi, Tokyo 202-8585, Japan



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